We introduce the Tree Tensor Network-enhanced Quantum-Classical Neural Network (TTN-QNet), a hybrid architecture that leverages the hierarchical structure of Tree Tensor Networks for efficient parameter representation and Variational Quantum Circuits (VQC) for expressive modeling. Unlike Tensor Ring Networks, TTNs reduce parameter redundancy through a tree-based topology, enabling scalable and interpretable computation. The proposed TTN-QNet is evaluated on the Iris, MNIST, and CIFAR-10 datasets, achieving classification accuracies of 93.2%, 85.24%, and 81.67%, respectively, on binary classification tasks. TTN-QNet demonstrates rapid convergence and robustness against barren plateaus, offering a promising direction for deep quantum learning.